Outi Mäkitie Selected Research

Autoantibodies

2/2024	Increased type 1 inflammation in gynecologic cervicovaginal samples in patients with APS-1.
12/2021	A gene-centric approach to biomarker discovery identifies transglutaminase 1 as an epidermal autoantigen.
1/2021	Endocrine Disorders and Genital Infections Impair Gynecological Health in APECED (APS-1).
1/2017	Diverse Autoantibody Reactivity in Cartilage-Hair Hypoplasia.

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Outi Mäkitie Research Topics

Disease

31	Osteoporosis 12/2023 - 01/2005
11	Osteogenesis Imperfecta (Lobstein Disease) 01/2021 - 05/2005
9	Neoplasms (Cancer) 04/2024 - 10/2012
8	Cartilage-hair hypoplasia 01/2021 - 07/2002
7	Infections 02/2024 - 01/2017
7	Hypogonadism (Hypergonadotropic Hypogonadism) 01/2020 - 10/2007
7	Obesity 01/2020 - 11/2015
6	Congenital Abnormalities (Deformity) 01/2021 - 03/2005
6	Vitamin D Deficiency 01/2021 - 10/2007
5	Inflammation (Inflammations) 02/2024 - 08/2013
5	Pseudohypoparathyroidism 01/2020 - 05/2015
5	Rickets (Rachitis) 01/2019 - 01/2016
4	Autoimmune Polyendocrinopathies (Schmidt Syndrome) 04/2024 - 01/2021
4	Chronic Disease (Chronic Diseases) 01/2024 - 01/2005
4	Hypersensitivity (Allergy) 01/2019 - 01/2016
4	Pain (Aches) 01/2019 - 06/2008
4	Hypophosphatemia 01/2019 - 02/2003
4	Hypocalcemia 01/2017 - 05/2015
4	Insulin Resistance 01/2017 - 05/2007
3	Birth Weight (Birth Weights) 10/2021 - 09/2015
3	Type 2 Diabetes Mellitus (MODY) 01/2020 - 01/2017
3	Osteomalacia 01/2019 - 01/2016
3	Pediatric Obesity 01/2018 - 01/2015
3	Hypercalcemia (Milk Alkali Syndrome) 01/2017 - 11/2012
3	Congenital Cortical Hyperostosis (Infantile Cortical Hyperostosis) 03/2014 - 05/2005
3	Compression Fractures (Compression Fracture) 07/2010 - 07/2007
2	type 1 Autoimmune polyendocrinopathy syndrome 12/2023 - 10/2021
2	Aplastic Anemia (Anemia, Hypoplastic) 01/2022 - 04/2013
2	Spontaneous Abortion (Miscarriage) 01/2022 - 11/2020
2	Ectopic Pregnancy 01/2022 - 11/2020
2	Disease Progression 01/2022 - 01/2019
2	Osteoarthritis 01/2022 - 01/2019
2	Addison Disease (Addison's Disease) 01/2021 - 11/2020
2	Pneumonia (Pneumonitis) 01/2021 - 01/2018
2	Head and Neck Neoplasms (Head and Neck Cancer) 11/2020 - 10/2012
2	Hypothyroidism 01/2020 - 05/2015
2	Familial Hypophosphatemic Rickets (X-Linked Hypophosphatemia) 01/2019 - 02/2003
2	Milk Hypersensitivity (Milk Allergy) 01/2019 - 01/2017
2	Spinal Fractures 01/2018 - 01/2012
2	Hyperphosphatemia 01/2017 - 05/2015
2	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2015 - 10/2011
2	Juvenile Arthritis (Juvenile Idiopathic Arthritis) 12/2014 - 04/2007
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 03/2014 - 01/2014
2	Secondary Hyperparathyroidism 01/2013 - 02/2003
2	Hypercalciuria 11/2012 - 03/2010
2	Cerebroretinal Microangiopathy with Calcifications and Cysts 03/2012 - 06/2011
2	Cysts 03/2012 - 06/2011
2	Leukoencephalopathies 03/2012 - 06/2011
2	Bone Resorption 05/2011 - 01/2009
2	Osteoporosis-pseudoglioma syndrome 04/2010 - 05/2005
2	Shwachman-Diamond Syndrome 10/2008 - 03/2008
2	Osteochondrodysplasias (Spondyloepiphyseal Dysplasia) 12/2005 - 10/2003

Drug/Important Bio-Agent (IBA)

25	Vitamin D FDA LinkGeneric 04/2024 - 10/2007
11	Diphosphonates (Bisphosphonates)IBA 12/2023 - 01/2005
9	CalciumIBA 01/2017 - 05/2011
7	GlucocorticoidsIBA 04/2024 - 01/2005
7	Collagen Type I (Type I Collagen)IBA 01/2022 - 05/2005
6	AntibodiesIBA 12/2023 - 05/2015
6	Parathyroid Hormone (Parathormone)IBA 01/2021 - 01/2013
6	Phosphates (Orthophosphate)IBA 01/2019 - 02/2003
5	RNA (Ribonucleic Acid)IBA 02/2024 - 07/2002
5	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2009
5	alpha2 Subunit Collagen Type IIBA 12/2020 - 05/2005
5	plastinIBA 10/2020 - 03/2015
5	Proteins (Proteins, Gene)FDA Link 01/2019 - 10/2010
4	AutoantibodiesIBA 02/2024 - 01/2017
4	LeptinIBA 01/2020 - 12/2014
4	Cholecalciferol (Vitamin D3)FDA Link 01/2018 - 11/2012
4	Low Density Lipoprotein Receptor-Related Protein-5IBA 04/2012 - 05/2005
3	Growth Hormone (Somatotropin)IBA 04/2024 - 01/2018
3	Alkaline PhosphataseIBA 01/2023 - 01/2009
3	25-hydroxyvitamin DIBA 01/2021 - 01/2016
3	hydroxide ionIBA 11/2020 - 09/2016
3	Immunoglobulin E (IgE)IBA 01/2019 - 01/2016
3	MineralsIBA 01/2017 - 10/2007
3	Glucose (Dextrose)FDA LinkGeneric 11/2015 - 05/2007
2	Ferritins (Ferritin)IBA 01/2022 - 04/2013
2	IronIBA 01/2022 - 04/2013
2	Untranslated RNA (Noncoding RNA)IBA 01/2021 - 01/2018
2	Hormones (Hormone)IBA 01/2021 - 01/2014
2	Teriparatide (Parathar)FDA Link 01/2021 - 01/2017
2	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 01/2020
2	MicroRNAs (MicroRNA)IBA 10/2020 - 01/2018
2	LigandsIBA 01/2020 - 01/2018
2	CateninsIBA 01/2020 - 08/2017
2	Calcitriol (Calcijex)FDA LinkGeneric 01/2019 - 02/2003
2	Estrogens (Estrogen)FDA Link 08/2018 - 07/2010
2	Testosterone (Sustanon)FDA Link 01/2018 - 01/2015
2	mitochondrial RNA-processing endoribonuclease (RNAse MRP)IBA 01/2017 - 07/2002
2	CollagenIBA 01/2017 - 05/2005
2	LipidsIBA 03/2014 - 05/2007
2	Retinaldehyde (Retinal)IBA 03/2012 - 06/2011
2	Pamidronate (Aredia)FDA LinkGeneric 01/2011 - 10/2007
2	Letrozole (Femara)FDA LinkGeneric 07/2010 - 01/2009

Therapy/Procedure

13	Therapeutics 01/2022 - 07/2010
4	Drug Therapy (Chemotherapy) 01/2022 - 01/2019
4	Stem Cell Transplantation 01/2020 - 07/2007
2	Aftercare (After-Treatment) 04/2024 - 01/2021
2	Induced Abortion (Induced Abortions) 01/2022 - 11/2020
2	Duration of Therapy 03/2015 - 02/2003